dbSNP build 132
- Intuitive representation of genomic variation using advanced web-based graphics (SVG)
- Search by HUGO gene symbol, dbSNP ID, internal CGF polymorphism ID, or chromosome coordinates
- “Gene-centric” display (only when a gene of interest is in view) oriented 5’ to 3’ regardless of the reference strand and adjacent genes
- Two views, a Locus Overview, which varies in size depending on the gene or genomic region being viewed and, below it, a Sequence View displaying 2000 base pairs within the overview
- Navigate the genome by clicking along the gene in the Locus Overview to change the Sequence View, expand or contract the genomic interval, or shift the view in the 5’ or 3’ direction (relative to the current gene)
- Lists of available genomic features
- Search for sequence matches in the Locus Overview
- Genomic features are represented by shape, color and opacity with contextual information visible when the user moves over or clicks on a feature
- Administrators can insert newly-discovered polymorphisms into the Genewindow database by entering annotations directly through the GUI
- Integration with a Laboratory Information Management System (LIMS) or other databases is possible
- Users can now filter SNPs by dbsNP submitter (e.g. HapMap SNPs) or by frequency.
- Population linkage disequilibrium and haplotype tagging SNPs, based on CGF data, will be displayed.
- Users will be able to download data from the web site based on the gene or genomic interval they are viewing.
Genewindow includes data from multiple public resources. As a result, the data presented can sometimes be incorrect or inconsistent. Genewindow does present validated data on polymorphisms from the CGF pipeline when available.